Bothwell to administer Pfizer Covid-19 third dose for immunocompromised

Following an order from the Missouri Department of Health and Senior Services (DHSS), Bothwell Regional Health Center will begin administering third doses of the Pfizer Covid-19 vaccine on Aug. 23 to certain immunocompromised individuals who have already received the two-dose Pfizer series. Individuals should wait at least 28 days between their second and third doses.

According to the DHSS order, a third dose of the PfizerNBioTech or Moderna vaccines may be administered to moderately to severely immunocompromised people due to a medical condition or combination of immunosuppressive medication or treatments including but not limited to the following:

  • Immunocompromised due to solid organ transplant and taking immune-suppressing medications
  • Immunocompromised due to active treatment for solid tumor and hematologic malignancies
  • Immune compromised due to Receipt of CAR-T cell or hematopoietic stem cell transplant (within two years of transplantation or taking immunosuppression therapy)
  • Moderate to severe primary immunodeficiency (e.g., DiGeorge, Wiskott-Aldrich Syndromes)
  • Immunocompromised due to Advanced or untreated HIV infection
  • Immunocompromised due to “Active treatment with high-dose corticosteroids or other drugs that may suppress immune response: high dose corticosteroids (i.e.., ≥ 20 mg prednisone or equivalent per day), alkylating agents, antimetabolites, transplant-related immunosuppressive drugs, cancer chemotherapeutic agents classified as severely immunosuppressive, tumor-necrosis (TNF) blocker or other biologic agents that are immunosuppressive or immunomodulatory”

Bothwell currently administers only the Pfizer Covid-19 vaccine. People who are eligible for the third dose may receive it at weekly clinics at Bothwell Healing Arts Center and Bothwell Health Center-Truman Lake in Warsaw; by walking in at the Bothwell Walk In Clinic; or by appointment at Bothwell Family Medicine Associates, Bothwell Family Health, Bothwell OB/GYN Associates, Bothwell Internal Medicine and Bothwell TLC Pediatrics.

While eligible individuals will not be required to provide documentation of their health status, they will be required to sign a new Covid-19 consent form as well as a form stating they qualify for the third dose and have received the two-dose series of the Pfizer vaccine. Clinic details and forms can be found at

People who received the two-dose series of the Moderna vaccine and are eligible for a third dose should contact the Pettis County Health Center. The order does not apply to those who received the Janssen/Johnson & Johnson vaccine.

The state order also indicates that individuals who do not meet the criteria for “moderately to severely immunocompromised” do not need a third dose at this time.